Endocrine Abstracts

Introduction: Hirsutism is a disease in which, women chin, upper lip, chest, abdomen, showing the terminal structure to increase hair growth in the male pattern of distribution as androgen sensitive back and thighs are seen. Neutrophil/lymphocyte ratio (NLR) has been proposed as a simple inflammatory marker of response. Increased value of NLR cardiovascular venture in patients was found to be an indicator of poor prognosis. In our study, we aimed to determine the association b...

Introduction: The aim of this study is to determine the relationship of Beck Depression Inventory (BDI) with vitamin D levels and total and visceral fat mass in cancer patients.Methods: A total of 219 patients were included in the study. All patients underwent blood tests including prealbumin, vitamin D. Also patients’ BMI values were calculated and total and visceral fat masses of all patients were measured by bio-impedance analyzer. All subjects c...

Acromegaly is known to be associated with both increased cardiovascular mortality and carbohydrate intolerance. The aim of our study is to compare intima-media thickness, a marker of atherosclerosis in active acromegalic patients with and without diabetes. 32 active acromegalic patients (M/ F: 15/17, 16 diabetic and 16 nondiabetic) were assessed for fasting blood glucose (FBG), insulin, growth hormone, insulin-like growth factor 1 and carotid intima-media thickness (IMT). Diab...

Increased heel pad thickness can be used as a marker of soft tissue enlargement in acromegalic patients. We aimed to investigate if concomittant hyperinsulinemia/and or diabetes secondary to insulin resistance in acromegaly contribute to the enlargement of heel pad. We compared heel pad thickness in 16 diabetic and 16 nondiabetic active acromegalic patients using X-ray images. All of the diabetics were well controlled with diet and/ or oral antidiabetic drugs. GH and IGF-1 wer...

Objective: The present study aimed to evaluate thyroid stimulating hormone (TSH) levels and anti-thyroid peroxidase antibodies (anti-TPOab) in euthyroid subjects with metabolic syndrome (MetS) and to compare them with healthy subjects without MetS.Design: Study included 173 subjects consisted of 96 subjects with MetS and 77 healthy controls. Gender, age, body mass index (BMI), waist circumfrence (WC), and detailed medical history of all participants were...

Introduction: Increased mean platelet volume (MPV) is an independent risk factor for thromboembolism, stroke and myocardial infarction. In this study we tried to emphasize the importance of gender difference in evaluation of relationship between MPV and serum biochemical parameters in type 2 diabetic patients.Methods: A total of 509 patients with diabetes mellitus who hospitalized due to several causes were retrospectively evaluated. Age, gender, other c...

Introduction: In this study we aimed to examine the risk factors associated with mortality of pneumonia among diabetic seniors in Turkish general population.Material and methods: After excluding individuals from other minorities, elderly diabetic patients who had been hospitalized due to pneumonia in recent three years consisted of study population. A total of 610 subjects aged 65 years or older were retrospectively analyzed and 196 patients who had no m...

Introduction: Rhabdomyolysis is usually attributed to trauma. However, there is an association of rhabdomyolysis with hyperosmolar states. It is also important to realize that hyperosmolar coma can be the presenting complaint of a diabetic seeking medical attention for the first time. In this case-report we aimed to present a patient with acute kidney injury due to rhabdomyolysis and hyperosmolar state.Case report: Forty nine-year-old black male patient ...

Aim: Euthyroid sick syndrome can be described as abnormal findings on thyroid function tests that occur in the setting of a nonthyroidal illness (NTI) without preexisting hypothalamic-pituitary and thyroid gland dysfunction. In this study we tried to compare thyroid function tests between patients with acute kidney injury (AKI) and healthy controls.Materials and Methods: This study consisted of 31 patients with AKI and 26 healthy controls. All patients&#...

Introduction: Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) belongs to TNF family and is released from inflammatory cells. It has been reported that TWEAK has several biological actions ranging from cell proliferation to stimulation of apoptosis. In in vitro studies, it was reported that TWEAK has alleviating effect on insulin resistance in hepatocytes. TWEAK decreases insulin resistance induced by TNF-a through activation of phosphatase 2A pathway in a...